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| Sibutramine is a neurotransmitter reuptake inhibitor that helps enhance satiety by inhibiting the reuptake of norepinephrine (by 54%), serotonin (by 53%), dopamine (by 16%). |
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| It was approved by the US Food and Drug Administration in November 97 for the treatment of obesity. | |
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| A large controlled-randomized study with over 9 thousands patients [scout] is currently ongoing to examine whether or not sibutramine reduces the risk for cardiovascular complications in people at high risk for heart disease. | |
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